Menopause and Perimenopause Consultation in Frankfurt am Main

A Proactive Approach to Hormonal Health

By 2030, 1.2 billion women are projected to reach menopause, a figure that will rise to 1.65 billion by 2050. Before this stage, between 60% and 80% of women from 34 to 51 years old face perimenopausal symptoms that diminish their quality of life and productivity. These symptoms can include everything from sleep issues and brain fog to anxiety and low energy. Often, they are not properly diagnosed or addressed. This situation affects families and carries a substantial economic burden through lost workdays, absenteeism, and women exiting the workforce.

The root cause is a decline in hormones. Women possess Estrogen (ER) and androgen (AR) receptors not just in reproductive organs (like the uterus, ovaries, and breast) but also in the brain, liver, kidneys, adipose tissue, bone, and immune cells. These receptors regulate functions spanning from bone density and metabolism to reproduction, cognitive ability, and mood.

You can think of these hormones as essential “building blocks.” The three main ones are:

Progesterone aka "the calm regulator": A drop in this hormone may lead to sleep disturbances, feelings of anxiety, and heavy menstrual bleeding.
Estrogen aka "the main character" Its reduction can affect brain function, causing memory issues or difficulty concentrating, and can also impact quality of life through joint pain and vasomotor symptoms like night sweats and hot flashes.
Testosterone aka the "the drive booster." A decrease in testosterone impacts motivation, libido, and the maintenance of muscle mass.

Smiling woman in black sweater representing perimenopause and menopause care

Key Differences Between Perimenopause and Menopause

Perimenopause

Often described as “the second puberty,” this term refers to the transitional phase of several years that precedes the final menstrual period.

Age of Onset: Usually begins at age 34 or later.
Definition: A period of transition brought on by diminishing ovarian function.
Duration: Typically extends for a period of 4 to 10 years.
Menstrual Cycle: Becomes inconsistent; periods may be lighter, heavier, shorter, longer, or missed altogether.
Hormone Levels: Progesterone is the first hormone to fall, whereas estrogen fluctuates unpredictably and testosterone shows a gradual decline. Diagnosis is typically made based on symptoms, not blood work.
Fertility: Pregnancy is still possible; it is advised to continue with your chosen method of birth control.
Key Symptoms: Sleep disturbances, fatigue, hot flashes, night sweats, mood fluctuations, anxiety, brain fog, joint pain or stiffness, muscle aches, vaginal dryness, reduced libido, and depressive feelings.

Menopause

Menopause represents a single moment in time that signifies the conclusion of the reproductive phase of life.

Age of Onset: Generally happens around the age of 51 (with a common range of 45–55).
Definition: A permanent milestone confirmed after twelve consecutive months have passed without a menstrual period.
Duration: A specific point in time. The period that follows this event is known as Postmenopause.
Menstrual Cycle: Has stopped completely.
Hormone Levels: Hormones stabilize at a consistently low level.
Fertility: It is no longer possible to become pregnant.
Key Symptoms & Risks: Symptoms like hot flashes and dryness may continue. There is an elevated risk of bone loss (osteoporosis) and a higher risk of dementia and Alzheimer’s disease for those not undergoing Hormone Replacement Therapy (HRT).

Symptoms of Perimenopause and Menopause Explained

Sleep Problems (50–55%): This covers insomnia, waking often during the night (WASO), and sleep that is not restorative. It is prompted by progesterone changes (which impact GABA receptors) and low estrogen that causes night sweats. The decrease in melatonin after age 40 further complicates this issue.
Low Energy and Fatigue (~80%): Estrogen helps manage cortisol and aids mitochondrial function. A reduction in estrogen results in metabolic stress and lower cellular energy, which frequently appears together with sleep issues.
Joint & Muscle Pain (65%): A loss of estrogen elevates pro-inflammatory cytokines, which causes systemic inflammation and less joint lubrication, resulting in stiffness or conditions like "frozen shoulder."
Brain Fog (60%): Neurons need estrogen to metabolize glucose. When levels drop, it induces a "hypometabolic" condition in the brain's memory areas (the hippocampus), which compromises concentration.
Hot Flashes & Night Sweats (50–55%): Estrogen helps control the hypothalamus (the body’s internal thermostat). Lower levels can cause the brain to incorrectly sense that the body is overheating, which activates abrupt cooling mechanisms.
Anxiety & Irritability (50–60%): Falling estrogen levels lower the production of serotonin (the "happiness hormone"), while decreasing progesterone lessens the brain's "calming" effect, resulting in heightened reactivity and mood fluctuations.
Abdominal Weight Gain (50%): The loss of estrogen heightens insulin resistance. The body then purposefully accumulates visceral fat in the abdominal region to try and manufacture estrone (a type of estrogen) from these fat cells.
Vaginal Dryness & Pain (40%): A reduction in estrogen diminishes blood flow, collagen, and elasticity within the pelvic tissues, which can cause atrophy and discomfort with intercourse (dyspareunia).
Low Libido (40–45%): This is caused by a significant drop in testosterone levels between the ages of 45 and 55, which is exacerbated by the physical discomfort and tiredness from low estrogen.
Depressive Symptoms (40–45%): During perimenopause, the likelihood of a new depressive episode rises by 2 to 4 times because of how estrogen affects the density of serotonin receptors in the brain.
Dry Skin & Urinary Problems (35–45%): These issues stem from the same decrease in collagen, moisture retention, and tissue elasticity that impacts the vaginal walls.

Woman in her 40s experiencing perimenopause or menopause symptoms, wearing turquoise sweater in natural light

Modern menopause and perimenopause clinic, The Longevity Practise, with patient consultation space and wellness equipment

The Longevity Practice: Our Philosophy and Next Steps

At The Longevity Practice, our approach is to identify potential risks before they escalate into health issues by utilizing early, precise diagnostics. Rather than reacting to illness, we formulate clear, individualized strategies to uphold long-term wellness. Our aim is to provide every patient with a thorough understanding of their own body, complemented by actionable steps they can implement immediately. With prevention and clarity as our foundation, we guide patients toward building a longer, healthier life.

Our Core Principles

Our main goal is to help individuals feel their absolute best at any age and to provide support for them to live longer, healthier lives. To make this possible, we adhere to several key principles:

Scientific Precision
Personalization
Prevention First
Clarity & Guidance
Long-Term Healthspan
Trust & Transparency

Note: Our methodology revolves around sustainable and non-invasive solutions. We concentrate on these core principles to facilitate lasting physiological correction and support long-term health management.

Next Steps

Find out if our approach is a good fit for you. Arrange your consultation online and Schedule an appointment

Evidence-based Longevity In Frankfurt am Main

In our practice, we rely exclusively on evidence-based methods and medical diagnostics that have been scientifically proven to make a difference. Our focus is on preventing the “four horsemen” of aging—cardiovascular disease, cancer, metabolic dysfunction, and neurodegeneration—rather than offering trends like epigenetic age tests or wellness drips. Our Prevention strategy addresses tailored exercises, nutrition, sleep, mental health and if necessary support by supplement and medication.

Cost Of Perimenopause And Menopause Focus Session In Frankfurt am Main

The cost for a Perimenopause and Menopause Focus Session is based on the German healthcare pricing system (GOÄ – Gebührenordnung für Ärzte). We encourage you not to stop at consultation alone, but to begin your full Longevity Journey with us. Here is what our protocol looks like:

Perimenopause and Menopause Focus Session

199€

Goal: Assess menopausal stage and symptom profile to evaluate disease risk associated with hormonal decline and determine optimal clinical interventions.

Duration: 45 minutes

Book appointment

Full Diagnostic Visit

1,399€

Goal: Establish a data-driven biological baseline to unlock personalized peak performance and long-term health optimization.

Duration: 3 hours

Book appointment

Introduction Session

0€

Schedule a quick video call to learn more about The Longevity Practice services and approach.

Duration: 15 minutes

Book Call

Testimonials

What our customers say about us

Pia, 45 – Menopause & Brain Fog

I thought I was losing my mind. I’d forget simple words in the middle of sentences. Realizing it was just the estrogen drop was a huge relief.

Anna, 49 – Menopause & Sleep

The night sweats were brutal—I was waking up drenched and exhausted every single night. I was so irritable with my family. Once I balanced my hormones, I finally got my sleep back.

Anita, 54 – Menopause & Anxiety

Nobody told me about the sudden heart palpitations and anxiety. I felt on edge for no reason. Learning it was hormonal made so much sense.

Julia, 46 – HRT & Strength

When I saw how much muscle mass I had lost, I finally understood why I felt weaker. It took longer than I expected to get my hormone levels properly adjusted, but once they were stable, my sleep and daily energy improved dramatically. Combining this with regular strength training has made me noticeably stronger and more resilient in everyday life.

Anne, 44 – HRT & Sleep

I never realized how much my hormones were affecting my sleep until I have taken progesterone. After adjusting my therapy and tracking my sleep for six weeks, I went from waking up four or five times a night to sleeping through almost every night. It’s such a relief to finally wake up feeling rested and ready for the day.