Woman smiling in natural sunlight representing wellness during perimenopause and menopause

Perimenopause & Menopause Consultation In Frankfurt

Fast appointments (self payers or privately insured patients only)

Online doctor consultations and testing at our office in Berlin Prenzlauer Berg

On-demand coaching from doctors for your current problems, needs and healthspan goals.

Anticipating Health Needs

By 2030, an estimated 1.2 billion women will reach menopause, a figure projected to rise to 1.65 billion by 2050. Before this stage, between 60% and 80% of women from 34 to 51 years of age endure perimenopausal symptoms that diminish their quality of life and work performance. These symptoms can include everything from sleep disturbances to cognitive haze, anxiety, and diminished energy. Frequently, these conditions remain undiagnosed and without treatment. The consequence is a substantial effect on families and a considerable economic burden stemming from missed work, employee absenteeism, and women exiting their careers.

This phenomenon is driven by a reduction in hormones. Women possess estrogen (ER) and androgen (AR) receptors not just in reproductive organs like the uterus, ovaries, and breast, but also in the brain, liver, kidneys, fat tissue, bones, and immune cells. These receptors play a role in processes ranging from bone mass and metabolic rate to reproductive capability, mental function, and emotional state.

Consider these hormones as essential “building blocks.” The three primary ones are:

  • Progesterone, also known as "the calm regulator": A decrease in this hormone can lead to disturbed sleep, feelings of anxiety, and excessive menstrual bleeding.
  • Estrogen, often called "the main character": Its reduction can affect cognitive processes, such as causing memory problems and concentration difficulties, or diminish quality of life through joint discomfort and vasomotor symptoms like night sweats and hot flashes.
  • Testosterone, referred to as "the drive booster": A drop in this hormone impacts one's motivation, sex drive, and muscle volume.
Smiling woman in black sweater representing perimenopause and menopause care
Chart showing estrogen, progesterone, testosterone and FSH hormone changes across perimenopause stages to menopause

Perimenopause and Menopause: Defining the Key Differences

Perimenopause

Frequently referred to as “the second puberty,” this transitional period is the multi-year stage that precedes the final menstrual period.

  • Beginning Age: Usually commences at 34 years of age or later.
  • Definition: A transitional phase initiated by the diminishing function of the ovaries.
  • Length: Typically spans from 4 to 10 years.
  • Menstrual Cycle: Turns irregular, with periods that can become lighter, heavier, shorter, longer, or be missed altogether.
  • Hormone Levels: Progesterone is the first hormone to decline, followed by unpredictable fluctuations in estrogen and a gradual reduction in testosterone. A diagnosis is typically made based on symptoms, not bloodwork.
  • Fertility: Pregnancy is still possible; continuing to use a preferred method of contraception is advised.
  • Primary Symptoms: Disturbed sleep, exhaustion, hot flashes, night sweats, mood fluctuations, anxiety, cognitive haze, joint pain or stiffness, muscle soreness, vaginal dryness, reduced libido, and symptoms of depression.

Menopause

Menopause refers to a distinct moment in time that signals the conclusion of a woman's reproductive phase.

  • Beginning Age: Generally happens at approximately 51 years of age (with a common range of 45–55).
  • Definition: A specific landmark confirmed after a woman has gone 12 months in a row without menstruating.
  • Length: A singular event. The period that comes after this point is known as Postmenopause.
  • Menstrual Cycle: Ceases entirely.
  • Hormone Levels: Hormonal levels stabilize at a consistently low baseline.
  • Fertility: It is no longer possible to become pregnant.
  • Primary Symptoms & Risks: Certain symptoms like hot flashes and dryness can continue. There is a heightened risk of bone density loss (osteoporosis), along with an increased risk for dementia and Alzheimer’s disease in individuals who do not use Hormone Replacement Therapy (HRT).

Symptoms of Perimenopause and Menopause and Their Hormonal Causes

  • Sleep Problems (50–55%): Encompasses insomnia, waking often during the night (WASO), and sleep that is not refreshing. This is caused by fluctuating progesterone levels (impacting GABA receptors) and reduced estrogen that leads to night sweats. A decrease in melatonin after age 40 also contributes to the problem.
  • Low Energy and Fatigue (~80%): Estrogen is responsible for managing cortisol and aiding mitochondrial activity. When it decreases, it results in metabolic stress and a reduction in cellular energy, which frequently happens in conjunction with sleep issues.
  • Joint & Muscle Pain (65%): A reduction in estrogen causes a rise in pro-inflammatory cytokines, which results in body-wide inflammation and less joint lubrication, causing symptoms like stiffness or "frozen shoulder".
  • Brain Fog (60%): Neurons need estrogen to utilize glucose for energy. Falling levels induce a "hypometabolic" condition in the brain's memory areas (the hippocampus), which compromises the ability to concentrate.
  • Hot Flashes & Night Sweats (50–55%): The hypothalamus, which acts as the body's internal thermostat, is regulated by estrogen. A drop in this hormone can make the brain incorrectly sense that the body is too hot, initiating abrupt cooling mechanisms.
  • Anxiety & Irritability (50–60%): Falling estrogen levels diminish the production of serotonin ("happiness hormone"), and decreasing progesterone lessens the brain's natural calming effect, resulting in heightened reactivity and fluctuating moods.
  • Abdominal Weight Gain (50%): The loss of estrogen heightens insulin resistance. In response, the body intentionally accumulates visceral fat around the abdomen in an effort to generate estrone (a type of estrogen) from these fat cells.
  • Vaginal Dryness & Pain (40%): A decrease in estrogen diminishes blood flow, collagen, and elasticity within the pelvic tissues, which can cause atrophy and painful intercourse (dyspareunia).
  • Low Libido (40–45%): This is caused by a significant drop in testosterone levels between the ages of 45 and 55, which is compounded by the physical discomfort and tiredness resulting from low estrogen.
  • Depressive Symptoms (40–45%): During perimenopause, the likelihood of developing depression for the first time rises by two to four times because of estrogen's effect on the density of serotonin receptors in the brain.
  • Dry Skin & Urinary Problems (35–45%): These issues stem from the same reduction in collagen, moisture retention, and tissue elasticity that impacts the vaginal tissues.
Woman in her 40s experiencing perimenopause or menopause symptoms, wearing turquoise sweater in natural light
Modern menopause and perimenopause clinic, The Longevity Practise, with patient consultation space and wellness equipment

Our Philosophy at The Longevity Practice and Getting Started

The Longevity Practice is dedicated to detecting health risks before they develop into problems by using early and accurate diagnostic methods. Rather than responding to illness, our approach is to develop straightforward, individualized strategies for preserving health over the long term. We aim to provide each patient with profound insight into their own body and actionable steps for immediate implementation. By prioritizing prevention and clear communication, we guide patients in constructing a longer, more healthful life.

Our Foundational Principles

Our main objective is to assist individuals in achieving optimal well-being at every stage of life and to help them live longer, healthier lives. To accomplish this goal, we adhere to a number of fundamental principles:

  • Scientific Precision
  • Personalization
  • Prevention First
  • Clarity & Guidance
  • Long-Term Healthspan
  • Trust & Transparency

Note: Our methodology is built around sustainable and non-invasive solutions. We concentrate on these core principles to facilitate enduring physiological adjustments and effective long-term health maintenance.

How to Proceed

Discover if our methods align with your needs. Book your consultation online and Schedule an appointment

Evidence-based Longevity In Frankfurt

In our practice, we rely exclusively on evidence-based methods and medical diagnostics that have been scientifically proven to make a difference. Our focus is on preventing the “four horsemen” of aging—cardiovascular disease, cancer, metabolic dysfunction, and neurodegeneration—rather than offering trends like epigenetic age tests or wellness drips. Our Prevention strategy addresses tailored exercises, nutrition, sleep, mental health and if necessary support by supplement and medication.

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Cost Of Perimenopause And Menopause Focus Session In Frankfurt

The cost for a Perimenopause and Menopause Focus Session is based on the German healthcare pricing system (GOÄ – Gebührenordnung für Ärzte). We encourage you not to stop at consultation alone, but to begin your full Longevity Journey with us. Here is what our protocol looks like:

Perimenopause and Menopause Focus Session
199€
Goal: Assess menopausal stage and symptom profile to evaluate disease risk associated with hormonal decline and determine optimal clinical interventions.
Duration: 45 minutes
Full Diagnostic Visit
1,399€
Goal: Establish a data-driven biological baseline to unlock personalized peak performance and long-term health optimization.
Duration: 3 hours
Introduction Session
0€
Schedule a quick video call to learn more about The Longevity Practice services and approach.
Duration: 15 minutes

Testimonials

What our customers say about us

Pia, 45 – Menopause & Brain Fog
I thought I was losing my mind. I’d forget simple words in the middle of sentences. Realizing it was just the estrogen drop was a huge relief.
Anna, 49 – Menopause & Sleep
The night sweats were brutal—I was waking up drenched and exhausted every single night. I was so irritable with my family. Once I balanced my hormones, I finally got my sleep back.
Anita, 54 – Menopause & Anxiety
Nobody told me about the sudden heart palpitations and anxiety. I felt on edge for no reason. Learning it was hormonal made so much sense.
Julia, 46 – HRT & Strength
When I saw how much muscle mass I had lost, I finally understood why I felt weaker. It took longer than I expected to get my hormone levels properly adjusted, but once they were stable, my sleep and daily energy improved dramatically. Combining this with regular strength training has made me noticeably stronger and more resilient in everyday life.
Anne, 44 – HRT & Sleep
I never realized how much my hormones were affecting my sleep until I have taken progesterone. After adjusting my therapy and tracking my sleep for six weeks, I went from waking up four or five times a night to sleeping through almost every night. It’s such a relief to finally wake up feeling rested and ready for the day.