A woman in black athletic wear exercising, representing physical vitality through hormone replacement therapy

Hormone Balancing in Jessen

Fast appointments (self payers or privately insured patients only)

Online doctor consultations and testing at our office in Berlin Prenzlauer Berg

On-demand coaching from doctors for your current problems, needs and healthspan goals.

Prevention Through Foresight

Post-menopause constitutes one-third of a woman's life, which is about 33 years based on an average menopause age of 51 and an EU life expectancy of 84. Additionally, women can experience perimenopausal symptoms for as long as 10 years. This means approximately half of a woman's life is spent managing a range of symptoms that can diminish both quality of life and personal productivity.

Individuals undergoing HRT (Hormone Replacement Therapy) often describe the experience as “feeling like themselves again”. Therefore, identifying the correct treatment frequency and dosage represents a significant investment in one's well-being for the upcoming 30-40 years of life.

Here is a simplified guide to help identify which hormone might be deficient:

  • Low Progesterone: Feelings of anxiety, irritation, and being 'wired' may occur.
  • Low Estrogen: You might experience sensations of dryness, heat, and tearfulness.
  • Low Testosterone: Symptoms can include fatigue, weakness, and a lack of motivation.

It is important to remember that each woman's experience with symptoms and their intensity is unique. Hormones can have overlapping or synergistic effects. Consequently, addressing and resolving symptoms is typically a gradual, iterative journey.

A medical graph showing fluctuating estrogen and testosterone levels managed by hormone replacement therapy
A woman meditating cross-legged in a bedroom, highlighting the mental wellness focus of hormone replacement therapy.

The Body-Wide Impact of Hormonal Imbalance

  • Sleep: Deficient Progesterone can lead to disrupted sleep and waking during the night (due to the loss of GABA's calming influence); low Estrogen can result in night sweats and waking up early in the morning.
  • Mood: Inadequate Progesterone can cause irritability and anxiety; insufficient Estrogen is associated with depression and anhedonia; low Testosterone can diminish motivation and assertiveness.
  • Menstrual Cycle: A Progesterone deficiency can result in heavy, erratic bleeding (from unopposed estrogen); a lack of Estrogen leads to shorter or missed menstrual periods.
  • Vasomotor Symptoms: Insufficient Estrogen is the main cause behind hot flashes and night sweats.
  • Libido & Sexual Function: Deficient Estrogen results in vaginal dryness and discomfort; low Testosterone is the principal reason for decreased spontaneous desire and less intense orgasms.
  • Cognitive Symptoms: A lack of Estrogen can lead to "brain fog" and memory issues; inadequate Testosterone can impair strategic thinking and mental focus.
  • Metabolism: Insufficient Estrogen encourages the accumulation of central fat (belly fat) and contributes to insulin resistance; low Testosterone leads to a reduction in lean muscle, which slows the metabolic rate.
  • Skin & Hair: Deficient Estrogen diminishes collagen levels and skin elasticity; a lack of Testosterone may play a role in thinning hair.
  • Bone & Muscle: Inadequate Estrogen is a significant factor in the development of osteoporosis and sarcopenia; low Testosterone decreases physical endurance and muscular power.
  • Urogenital Health: Insufficient Estrogen can cause Genitourinary Syndrome of Menopause, which involves symptoms like atrophy, itching, and recurrent UTIs.

Understanding the Treatment Process

Hormone Replacement Therapy is a personalized and evolving process, customized to your individual biological needs. Unlike a standard prescription, your physician will modify doses and schedules according to blood test results and your symptom log. The usual approach involves stabilizing one hormone at a time before adding the next, with follow-up appointments scheduled every 3–6 months.

  • Progesterone (Oral Micronized): Derived from plants, bioidentical progesterone is readily absorbed by the body. Its advantages include safeguarding the uterine lining, stabilizing hormones, alleviating anxiety, and enhancing sleep quality. The typical protocol involves 100mg–200mg taken at bedtime to accommodate its sedative effect. Women in perimenopause generally use it in the latter half of their cycle (days 14–28), while those with erratic cycles or who are post-menopausal take it on a continuous basis.
  • Estradiol (Transdermal): Application methods that go through the skin, like gels/patches, present a safer alternative to oral estrogen. While oral estrogen can quadruple the risk of blood clots, studies (e.g., BMJ 2019) show transdermal use carries no such increased risk as the hormone is absorbed directly through the skin into the bloodstream. Gels are often the first choice for simple dose adjustments, and it generally requires 4–8 weeks of regular application before symptoms begin to improve.
  • Transdermal Testosterone: While testosterone can enhance libido and energy levels, formulas specifically for women are not widely available outside of Australia. The dose is kept very low (approx. 300mcg/day) because higher amounts can lead to side effects like acne or unwanted hair growth.
  • Dehydroepiandrosterone (DHEA): This is occasionally used as a hormonal precursor, though its effectiveness when taken orally can be variable. It's important to note that vaginal DHEA is intended only for treating localized atrophy and does not serve as a systemic hormone replacement.
  • Medical Supervision: Every form of HRT must be prescribed and managed under the guidance of a qualified medical professional.
A healthcare professional in a white blouse providing expert hormone replacement therapy guidance in a modern office.
Abstract pink and blue swirling textures symbolizing complex biological changes during hormone replacement therapy.

What to Expect: The HRT Timeline

  • First Few Weeks You may begin to experience slight relief from symptoms, including better sleep, an improved mood, or more energy. The timing of this relief varies based on the initial hormone used. Progesterone tends to work more quickly, whereas Estradiol typically needs a minimum of 2 to 4 weeks for initial effects to become noticeable. This period is also for establishing a personal application routine—determining the best time, method, and location.
  • 1 to 3 Months The dosage is evaluated during this time, as the therapy is customized based on your specific symptoms. The dose is increased if symptoms return. If side effects like breast tenderness or migraines develop, the estrogen dose is typically reduced. In an ideal scenario, mood fluctuations begin to even out and energy levels rise. The occurrence of symptoms such as hot flashes or night sweats should lessen.
  • 3 to 6 Months Most individuals report substantial relief in this timeframe, as transdermal Estradiol and Testosterone require more time to produce their full effects. Symptoms like hot flashes, night sweats, and vaginal dryness frequently show marked improvement, and mood swings occur far less often.
  • 6 to 12 Months At this stage, you are experiencing the complete benefits of the therapy and can observe a significant enhancement in your quality of life. You also recognize that adjustments may still be necessary and are able to modify dosages or methods of administration as needed.
  • Month 13 Onwards Over the long term, further advantages continue to build, such as increased bone strength (which lowers the risk of osteoporosis) and improved cardiovascular health, contributing to your overall well-being as you get older. It is important to note that these long-term benefits are most effective when combined with strength training, a nutritious diet, and adequate protein consumption.

Next Steps

At The Longevity Practice, our focus is on detecting risks before they evolve into health issues by using early and accurate diagnostics. Rather than responding to illness after it occurs, we develop straightforward, individualized strategies for preserving long-term health. We aim to provide each patient with profound insight into their own body and actionable steps for immediate implementation. By centering our approach on prevention and clarity, we empower patients to construct a longer, more healthful life.

Find out if our methodology is a good fit for your needs. You can book your consultation on our website and Schedule an appointment

Evidence-based Longevity In Jessen

In our practice, we rely exclusively on evidence-based methods and medical diagnostics that have been scientifically proven to make a difference. Our focus is on preventing the “four horsemen” of aging—cardiovascular disease, cancer, metabolic dysfunction, and neurodegeneration—rather than offering trends like epigenetic age tests or wellness drips. Our Prevention strategy addresses tailored exercises, nutrition, sleep, mental health and if necessary support by supplement and medication.

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Cost Of A Hormone Replacement Therapy Focus Session In Jessen

The cost for a Hormone Replacement Therapy Focus Session is based on the German healthcare pricing system (GOÄ – Gebührenordnung für Ärzte). We encourage you not to stop at consultation alone, but to begin your full Longevity Journey with us. Here is what our protocol looks like:

Hormone Replacement Therapy Focus Session
199€
Goal: Conduct a comprehensive hormone panel and risk-benefit analysis to develop a personalized HRT protocol and targeted treatment strategy.
Duration: 45 minutes
Full Diagnostic Visit
1,399€
Goal: Establish a data-driven biological baseline to unlock personalized peak performance and long-term health optimization.
Duration: 3 hours
Introduction Session
0€
Schedule a quick video call to learn more about The Longevity Practice services and approach.
Duration: 15 minutes

Testimonials

What our customers say about us

Julia, 46 – HRT & Strength
When I saw how much muscle mass I had lost, I finally understood why I felt weaker. It took longer than I expected to get my hormone levels properly adjusted, but once they were stable, my sleep and daily energy improved dramatically. Combining this with regular strength training has made me noticeably stronger and more resilient in everyday life.
Anna, 44 – HRT & Sleep
I never realized how much my hormones were affecting my sleep until I have taken progesterone. After adjusting my therapy and tracking my sleep for six weeks, I went from waking up four or five times a night to sleeping through almost every night. It’s such a relief to finally wake up feeling rested and ready for the day.
Pia, 45 – Menopause & Brain Fog
I thought I was losing my mind. I’d forget simple words in the middle of sentences. Realizing it was just the estrogen drop was a huge relief.
Anna, 49 – Menopause & Sleep
The night sweats were brutal—I was waking up drenched and exhausted every single night. I was so irritable with my family. Once I balanced my hormones, I finally got my sleep back.
Anita, 54 – Menopause & Anxiety
Nobody told me about the sudden heart palpitations and anxiety. I felt on edge for no reason. Learning it was hormonal made so much sense.